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North Carolina Immunization Branch

Healthcare Providers

New and Noteworthy


The North Carolina Immunization Branch, in conjunction with the Centers for Disease Control and Prevention (CDC) is issuing this release due to a recent increase in the number of measles cases nationwide. CDC has reported 47 more measles cases, raising the total since the first of the year to 206 cases in 11 states. For comparison, the CDC reported 372 cases for all of 2018, the most since 2014. Affected states are California, Colorado, Connecticut, Georgia, Illinois, Kentrucky, New Jersey, New York, Oregon, Texas, and Washington.Five outbreaks (defined as 3 or more linked cases) have been reported, in Rockland County, New York; Monroe County, New York; New York City; Washington; Texas; and Illinois. Of these outbreaks, two are still ongoing from 2018. NC reported three cases in 2018, and has reported none so far for 2019.

This communication also intends to serve as a reminder that vaccination against measles is the best way to prevent the spread of the disease. CDC urges healthcare professionals to ensure that all patients are up to date on MMR vaccine, including before international travel.

What Should Clinicians Do?

  • Discuss the importance of MMR vaccine with parents. Listen and respond to parents’ questions. When parents have questions, it does not necessarily mean they won’t accept vaccines. Sometimes, they simply want your answers to their questions.
  • Ensure all patients are up to date on measles, mumps, rubella (MMR) vaccine.
  • Children need 2 doses of MMR: one dose at 12-15 months and another dose at 4-6 years.
  • Before any international travel, infants 6-11 months need 1 dose of MMR vaccine, children 12 months and older need 2 doses separated by at least 28 days, and teenagers and adults who do not have evidence of immunity against measles need 2 doses separated by at least 28 days.
  • Consider measles in patients presenting with febrile rash illness and clinically compatible measles symptoms (cough, coryza, and conjunctivitis), and ask patients about recent travel internationally or to domestic venues frequented by international travelers, as well as a history of measles exposures in their communities.
  • Promptly isolate patients with suspected measles to avoid disease transmission and immediately report the suspect measles case to the health department.
  • Obtain specimens for testing from patients with suspected measles, including viral specimens for genotyping, which can help determine the source of the virus. Contact the local health department with questions about submitting specimens for testing.
  • For more information, please visit:

  • Measles for Healthcare Professionals for patient evaluation, diagnosis and management guidelines
  • Provider Resources for Vaccine Conversations with Parents, which aim to strengthen communication between healthcare professionals and parents
  • For information to share with parents, please visit:

  • Measles: Make Sure Your Child is Fully Immunized for a recent article for parents about measles
  • Educational Resources for Parents and Childcare Providers for resources to share with parents, including printable fact sheets, posters, and printable infographics
  • Below is additional information about measles for healthcare professionals:

  • NC DHHS Communicable Disease Branch Measles Information
  • TEDMED at CDC:Measles-Making a Disease Disappear conference talk from 2013
  • CDC Expert Commentary video on Medscape about measles

*Preliminary data reported to CDC.

Please contact the NCIR Helpdesk with any questions by phone: 1-877-USE-NCIR (873-6247) or by email:

  • NCIP Provider Resource Guide
  • FAQs on Changes to the NCIP (PDF, 35 KB)
  • Click here to review North Carolina Immunization Rules and Laws.
  • A short video on the correct technique for intramuscular injection.
  • Getting a flu vaccine every year is the best way to protect yourself and your family from flu and its potentially serious complications. CDC recommends that everyone 6 months and older get vaccinated by the end of October.
  • Did you know? That anyone even young, healthy adults can get sick from the flu and spread it to others. Buzz buzz (text message: You coming out tonight? I can't I have the flu. My niece and girlfriend have it now too.) The short time it will take you to get a flu vaccine. Can help protect you and the ones you love. The flu vaccine is safe and does not cause the flu. #FightFlu

Provider Education

Earn continuing education credits through trainings offered by the N.C. Immunization Branch and others.  Access online guides for the NCIR and more.

North Carolina Immunization Program (NCIP) Requirements

Review the basics of the NCIP, learn how to join and what’s required of an enrolled provider. Access links to important documents like the NCIP Coverage Criteria, memos from the Immunization Branch, vaccine storage and handling resources, vaccine information statements and resources on reporting vaccine preventable diseases in North Carolina.

NCIP Provider Resource Guide

A printable guide to everything you need to know about the NCIP and NCIR.

i. Table of Contents (PDF, 19 KB) (Updated June 2018)
I. Contact Information (PDF, 1.26 MB) (Updated January 2018)
II. NCIP Program Information (PDF, 794 KB) (Updated January 2018)
III. Clinical/Administrative Information (PDF, 7.2 MB) (Updated January 2019)
IV. Storage & Handling (PDF, 3.57 MB) (Updated October 2018))
V. Communicable Disease Reporting & Law (PDF, 1.24 MB) (Updated January 2018)
VI. Resources (PDF, 64 KB) (Updated January 2018)
VII. North Carolina Immunization Registry (NCIR) (PDF, 1.09 MB) (Updated January 2018)

North Carolina Immunization Registry (NCIR)

Learn about the NCIR and how it can help your practice track immunizations and identify patients who need vaccinations. 


View and download important documents like VAL forms, reminder/recall post cards and access clinical tools created by the N.C. Immunization Branch and others.