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North Carolina Immunization Branch

NCIR Promoting Interoperability

North Carolina Local Implementation Guide (NCLIG)

North Carolina HL7 Version 2.5.1 Local Implementation Guide Updated 02/23/24

Links to additional resources are listed below:

Onboarding Resources

Frequently Asked Questions

Please review the FAQs below before contacting the N.C. Immunization Branch. If you do not find a response to your question, please send your question in an e-mail to the Data Exchange Help Desk. The intended audience for this FAQ are provider organizations as well as electronic health records (EHR) vendor personnel.

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Provider Registration

 1. Do I need to register?

The Registration Portal is for those who administer immunizations and intend to submit immunization information electronically.

 2. I already registered, do I need to register again?

Once you have registered and received confirmation, there is no need to re-register.

 3. When will I be invited to onboard?

NCIR will invite providers to onboard after all readiness requirements, including demonstration of technical readiness have been met.

 4. What do I do if I never received the notification?

Registration notification is provided for those who have completed registration. To confirm if you have completed your registration, please log into the registration portal.

 5. How is onboarding order determined?

Onboarding order is based on technical readiness.

Please review the FAQs below before contacting the N.C. Immunization Branch. If you do not find a response to your question, please send your question in an e-mail to the Data Exchange Help Desk. The intended audience for this FAQ are provider organizations as well as electronic health records (EHR) vendor personnel.

Technical Readiness

 1. Do I (the provider) need to be involved in technical readiness?

Although the provider and clinical staff do not have an active part in technical testing, it is still useful to know what stage of the process your organization is in, and what work is being done toward onboarding completion.

 2. Why do we need to sign a confidentility agreement?

The nature of immunization information being exchanged falls under HIPAA. Because of this we require an agreement that adheres to and complies with HIPAA, as well as adherence to the proper user of the NCIR.

 3. What methods of connections is available?

  • Direct connection NCIR
  • HIEA passthrough to NCIR

Please review the questions below before contacting the N.C. Immunization Branch. If you do not find a response to your question, please send your question in an e-mail to the Data Exchange Help Desk. The intended audience for this FAQ are provider organizations as well as electronic health records (EHR) vendor personnel.

Provider Onboarding

 1. What is a MOU?

A MOU or Memorandum of Understanding is a formal agreement between two or more parties to establish official partnerships. This MOU is between NCIR and the provider to ensure onboarding is completed by a determined timeline.

 2. Who needs to attend the kick-off call?

The kick-off call should be attended by those who will be involved in technical testing (vendor and technical staff), clinical testing (providers doing the testing), and those in charge of project management and go-live monitoring.

 3. What is covered in the testing manual?

There are two distinct areas in the testing manual to cover not only different functionality, but scenarios.

VXU clinical testing shows the ability of clinicians to record immunizations (new and historical), record client comments, contraindications, and submit relevant demographic and eligibility information.

QBP clinical testing allows the clinicians to query the NCIR for patient information, updating their own records, and being able to verify information sent from the NCIR.

 4. Why do clinical staff conduct testing?

Clinical staff conduct clinical testing to provide training on the updated features of the interface and new workflow, as well as provide the familiarity with solely using their EHR to place and administer immunizations without logging into the NCIR.

 5. What is the timeline for clinical testing?

The NCIR understands the time demands on clinicians, our average time to pass all VXU and QBP test scenarios is two weeks.

Acronym Reference


Click on the link for a list of helpful acronyms used within the IIS community.

June 2019 - NCIR was recognized for meeting the Immunization Information System (IIS) Measurement Content of Transport for 2019 AIRA Certificate of Validation for Transport Complete 2019